User profiles for S. Freund

Stephen Freund

Computer Science, Williams College
Verified email at cs.williams.edu
Cited by 5095

FastTrack: efficient and precise dynamic race detection

C Flanagan, SN Freund - ACM Sigplan Notices, 2009 - dl.acm.org
… Although FASTTRACK does not currently support the full set of concurrency primitives
available in the Java concurrency library [37], we believe their effects on a program’s happens-…

Phage-encoded combinatorial chemical libraries based on bicyclic peptides

C Heinis, T Rutherford, S Freund, G Winter - Nature chemical biology, 2009 - nature.com
Here we describe a phage strategy for the selection of ligands based on bicyclic or linear
peptides attached covalently to an organic core. We designed peptide repertoires with three …

The complete folding pathway of a protein from nanoseconds to microseconds

…, JG Grossmann, S Sato, GS Jas, SMV Freund… - Nature, 2003 - nature.com
Combining experimental and simulation data to describe all of the structures and the
pathways involved in folding a protein is problematical. Transition states can be mapped …

Type-based race detection for Java

C Flanagan, SN Freund - Proceedings of the ACM SIGPLAN 2000 …, 2000 - dl.acm.org
This paper presents a static race detection analysis for multithreaded Java programs. Our
analysis is based on a formal type system that is capable of capturing many common …

[HTML][HTML] OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis

…, Y Kulathu, T Wauer, F El Oualid, SMV Freund… - Cell, 2013 - cell.com
… The linkage specificity in OTU DUBs can be exploited in Ub chain restriction analysis,
whereby linkage-specific DUBs are used to identify the linkage type(s) on a ubiquitinated protein. …

Atomizer: a dynamic atomicity checker for multithreaded programs

C Flanagan, SN Freund - ACM SIGPLAN Notices, 2004 - dl.acm.org
… This analysis combines ideas from both Lipton’s theory of reduction and earlier dynamic
race detectors. Experience with a prototype checker for multithreaded Java code demonstrates …

[HTML][HTML] RNA recognition by a Staufen double-stranded RNA-binding domain

…, J Adams, DR Micklem, MR Proctor, S Freund… - The EMBO …, 2000 - embopress.org
The double-stranded RNA-binding domain (dsRBD) is a common RNA-binding motif found
in many proteins involved in RNA maturation and localization. To determine how this domain …

[HTML][HTML] The solution structure of the S1 RNA binding domain: a member of an ancient nucleic acid–binding fold

M Bycroft, TJP Hubbard, M Proctor, SMV Freund… - Cell, 1997 - cell.com
The S1 domain, originally identified in ribosomal protein S1, is found in a large number of
RNA-associated proteins. The structure of the S1 RNA-binding domain from the E. coli …

Natural genetic variation of freezing tolerance in Arabidopsis

MA Hannah, D Wiese, S Freund, O Fiehn… - Plant …, 2006 - academic.oup.com
Low temperature is a primary determinant of plant growth and survival. Using accessions of
Arabidopsis (Arabidopsis thaliana) originating from Scandinavia to the Cape Verde Islands, …

A role for the ESCRT system in cell division in archaea

RY Samson, T Obita, SM Freund, RL Williams, SD Bell - Science, 2008 - science.org
… of a target gene in S. solfataricus (21) (figs. S9 to S11). We transformed S. solfataricus with
either … (A to C) Phase contrast and fluorescent microscopy of DAPI-stained S. solfataricus cells …