Pancreatic cancer is a highly fatal disease with a 5-year survival rate of approximately 10%
in the USA, and it is becoming an increasingly common cause of cancer mortality. Risk …

Antibodies are important therapeutic agents for cancer. Recently, it has become clear that
antibodies possess several clinically relevant mechanisms of action. Many clinically useful …

Signal transducers and activators of transcription (STATs) comprise a family of cytoplasmic
transcription factors that mediate intracellular signaling that is usually generated at cell …

Cancer immunotherapies under development have generally focused on either stimulating
T cell immunity or driving antibody-directed effector functions of the innate immune system …

Over the past decade, the clinical utility of monoclonal antibodies has been realized and
antibodies are now a mainstay for the treatment of cancer. Antibodies have the unique capacity …

… Han, GGZ Zhang, DJW Grant, and R. Suryanarayanan. In situ dehydration of carbamazepine
… Han and R. Suryanarayanan. A method for the rapid evaluation of the physical stability of …

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a high degree of inflammation
and profound immune suppression. Here we identify Yes-associated protein (Yap) as a …

… Author links open overlay panel Rohit Surana a b , Sakshi Sikka a b , Wanpei Cai a b , Eun
Myoung Shin a , Sudha R. Warrier c , Hong Jie Gabriel Tan a , Frank Arfuso d f , Simon A. Fox …

Urease, a major virulence factor for Cryptococcus neoformans, promotes lethal meningitis/encephalitis
in mice. The effect of urease within the lung, the primary site of most invasive …

Gastric cancer (GC) is a lethal malignancy and the second most common cause of cancer-related
deaths. Although treatment options such as chemotherapy, radiotherapy, and surgery …