This thesis presents three studies in finance. The first paper compares the profitability of inside
transactions on specialist and dealer markets. It has been argued that fragmented dealer …

We investigate a potential source of profit to convertible bond arbitrageurs that is new to the
literature: anticipatory hedging in advance of convertible bond issues. When the reference …

How are ions distributed in the three-dimensional (3D) volume confined in a nanoscale
compartment? Regulation of ionic flow in the intracellular milieu has been explained by different …

The S2 domain of the spike glycoprotein from SARS-CoV is responsible for driving viral and
host cell membrane fusion. An internal fusion peptide (SARSIFP), located near the S2 …

… most successful approaches for protein structure modeling: fragment recombination (ROSETTA
method1) into a single protocol that employs fragmentary NMR data: Chemical Shifts, J-…

Despite the growing use of poxvirus vectors as vaccine candidates for multiple pathogens
and cancers, their innate stimulatory properties remain poorly characterized. Here we show …

The wax ester (WE) and triacylglycerol (TAG) biosynthetic potential of marine microorganisms
is poorly understood at the microbial community level. The goal of this work was to …

… Fernanda Pascutti4, Marie-Louise van der Hoorn3, 6 Michael Eikmans4, Sander de Kivit1,
and Jannie Borst1,* 7 8 … Stockis J, et al. Role of GARP in the activation of latent TGF-β1 …

The Bruton’s tyrosine kinase inhibitor ibrutinib is a highly effective, new targeted therapy for
chronic lymphocytic leukemia (CLL) that thwarts leukemia cell survival, growth, and tissue …

The encouraging results of the RV144 vaccine trial have spurred interest in poxvirus prime-protein
boost human immunodeficiency virus (HIV) vaccine modalities as a strategy to induce …