Targeting the RB-E2F pathway in breast cancer

J Johnson, B Thijssen, U McDermott, M Garnett… - Oncogene, 2016 - nature.com
Mutations of the retinoblastoma tumor-suppressor gene (RB1) or components regulating the
CDK-RB-E2F pathway have been identified in nearly every human malignancy. Re-…

Bitcoin research across disciplines

M Holub, J Johnson - The information society, 2018 - Taylor & Francis
Over the last few years, research on Bitcoin and other cryptocurrencies has snowballed across
many disciplines: technical fields, economics, law, public policy, finance, accounting, and …

Insight in first-episode psychosis

JP McEVOY, J Johnson, D Perkins… - Psychological …, 2006 - cambridge.org
Background. We report here a study examining the relationships between insight and
psychopathology, cognitive performance, brain volume and co-morbid depression in 251 patients …

[HTML][HTML] Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort

…, A Plough, MG Lorenzo, JL Panza, J Johnson… - Journal of Allergy and …, 2018 - Elsevier
Background Early introduction of dietary peanut in high-risk infants with severe eczema,
egg allergy, or both prevented peanut allergy at 5 years of age in the Learning Early About …

Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb–Raf-1 interaction as a novel target for metastatic disease

JL Johnson, S Pillai, D Pernazza, SM Sebti… - Cancer research, 2012 - AACR
The retinoblastoma (Rb)–E2F transcriptional regulatory pathway plays a major role in cell-cycle
regulation, but its role in invasion and metastasis is less well understood. We find that …

Money laundering: has the financial action task force made a difference?

J Johnson, YC Desmond Lim - Journal of Financial Crime, 2003 - emerald.com
Examines the involvement of the banking sector in money laundering over the last two decades,
in particular the relationship between banks and money laundering when governments’ …

Homophobia in the therapist and gay or lesbian client: Conscious and unconscious collusions in self-hate.

SS McHenry, JW Johnson - Psychotherapy: Theory, Research …, 1993 - psycnet.apa.org
Explores from a psychodynamic perspective negative biases (NBs) that interfere with or
negatively impact the functioning of the gay or lesbian client. Therapist NBs are subsumed under …

[HTML][HTML] Genetic and biochemical alterations in non-small cell lung cancer

JL Johnson, S Pillai, SP Chellappan - Biochemistry research …, 2012 - hindawi.com
Despite significant advances in the detection and treatment of lung cancer, it causes the
highest number of cancer-related mortality. Recent advances in the detection of genetic …

Small molecule regulators of Rb–E2F pathway as modulators of transcription

S Singh, J Johnson, S Chellappan - Biochimica et Biophysica Acta (BBA) …, 2010 - Elsevier
The retinoblastoma tumor suppressor protein, Rb, plays a major role in the regulation of
mammalian cell cycle progression. It has been shown that Rb function is essential for the proper …

The necessary illegitimacy of the whistleblower

KR Sawyer, J Johnson, M Holub - Business & Professional Ethics Journal, 2010 - JSTOR
This article examines the plight of the whistleblower using elements of organizational legitimacy
theory. In recognizing the negative correlation between the actions of the organization …