Androgens are critical steroid hormones that determine the expression of the male phenotype,
including the outward development of secondary sex characteristics as well as the …

This study investigated the optimization of CNC turning operation parameters for SKD11 (JIS)
using the Grey relational analysis method. Nine experimental runs based on an …

Many methods based on spectrophotometric, fluorometric, piezoresistive, amperometric or
conductive measurements have been proposed for detecting the concentration of …

… Compound 11 was also treated with various secondary amines to give C-6 aminomethyl
substituted intermediates 16a – 16e respectively which was converted to C-11 aminoalkoxy …

… c mouse, into healthy Balb/c as autograft tumor model. Then, we pre-treated tumor-bearing
mice with TCH-3562 (3 mg·kg −1 ·day −1 ) daily for two days, and then ip injected CPT-11 (50 …

Although the quinoline ring is found in a wide variety of biologically active compounds and is
frequently condensed with various heterocycles, synthesis and biological evaluation of the …

Most patients diagnosed with resected pancreatic adenocarcinoma (PDAC) survive less
than 5 years, but a minor subset survives longer. Here, we dissect the role of the tumor …

… Alkylation of 9a and 9b with K 2 CO 3 and a 4‘-substituted 2-bromoacetophenone gave
their respective N-[2-oxo-2-(4-substituted-phenyl)ethyl] derivatives 10a−c which were then …

The epithelial–mesenchymal transition (EMT), one of the main mechanisms underlying
development of cancer metastasis, induces stem-like properties in epithelial cells. Bmi1 is a …

The present report describes the synthesis and antiproliferative evaluation of certain 4-anilino-8-methoxy-2-phenylquinoline
and 4-anilino-8-hydroxy-2-phenylquinoline derivatives. The …