User profiles for Artur Rodrigues

Artur Filipe Rodrigues

Center for Neuroscience and Cell Biology, University of Coimbra
Verified email at cnc.uc.pt
Cited by 1060

Bacterial cellulose membranes as transdermal delivery systems for diclofenac: in vitro dissolution and permeation studies

NHCS Silva, AF Rodrigues, IF Almeida, PC Costa… - Carbohydrate …, 2014 - Elsevier
Bacterial cellulose (BC) membranes were explored as novel nanostructured transdermal
delivery systems for diclofenac sodium salt (a typical non-steroidal anti-inflammatory drug). …

Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic

…, M Fielden, C Vogt, L Newman, AF Rodrigues… - Nanoscale, 2018 - pubs.rsc.org
Neutrophils were previously shown to digest oxidized carbon nanotubes through a
myeloperoxidase (MPO)-dependent mechanism, and graphene oxide (GO) was found to undergo …

[HTML][HTML] Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells

…, FM Marincola, F Sgarrella, AF Rodrigues… - Nature …, 2017 - nature.com
Understanding the biomolecular interactions between graphene and human immune cells
is a prerequisite for its utilization as a diagnostic or therapeutic tool. To characterize the …

Live imaging of label-free graphene oxide reveals critical factors causing oxidative-stress-mediated cellular responses

S Vranic, AF Rodrigues, M Buggio, L Newman… - ACS …, 2017 - ACS Publications
The interest in graphene and its translation into commercial products has been expanding
at a high pace. Based on previously described pulmonary safety concerns for carbon …

A blueprint for the synthesis and characterisation of thin graphene oxide with controlled lateral dimensions for biomedicine

AF Rodrigues, L Newman, N Lozano… - 2D …, 2018 - iopscience.iop.org
Graphene-based materials (GBMs) have ignited a revolution in material science and technology,
with electronic, optical and mechanical properties that are of relevant interest for a wide …

[HTML][HTML] Engineering optical tools for remotely controlled brain stimulation and regeneration

AF Rodrigues, C Rebelo, T Reis, S Simões… - Biomaterials …, 2023 - pubs.rsc.org
Neurological disorders are one of the world’s leading medical and societal challenges due
to the lack of efficacy of the first line of treatments. Although pharmacological and non-…

The effects of extensive glomerular filtration of thin graphene oxide sheets on kidney physiology

…, J McCaffrey, C Ménard-Moyon, AF Rodrigues… - ACS …, 2016 - ACS Publications
Understanding how two-dimensional (2D) nanomaterials interact with the biological milieu
is fundamental for their development toward biomedical applications. When thin, …

[PDF][PDF] Graphene oxide elicits membrane lipid changes and neutrophil extracellular trap formation

…, B Lazzaretto, K Hultenby, L Newman, AF Rodrigues… - Chem, 2018 - cell.com
Understanding the biological interactions of graphene-based materials is important for the
safe use of these materials. Previous studies have explored the interaction between graphene …

Size‐dependent pulmonary impact of thin graphene oxide sheets in mice: toward safe‐by‐design

AF Rodrigues, L Newman, D Jasim… - Advanced …, 2020 - Wiley Online Library
Safety assessment of graphene‐based materials (GBMs) including graphene oxide (GO) is
essential for their safe use across many sectors of society. In particular, the link between …

[PDF][PDF] Microglia dysfunction caused by the loss of rhoa disrupts neuronal physiology and leads to neurodegeneration

R Socodato, CC Portugal, T Canedo, A Rodrigues… - Cell Reports, 2020 - cell.com
Nervous tissue homeostasis requires the regulation of microglia activity. Using conditional
gene targeting in mice, we demonstrate that genetic ablation of the small GTPase Rhoa in …