Update of the stroke therapy academic industry roundtable preclinical recommendations

M Fisher, G Feuerstein, DW Howells, PD Hurn, TA Kent… - Stroke, 2009 - Am Heart Assoc
The initial Stroke Therapy Academic Industry Roundtable (STAIR) recommendations published
in 1999 were intended to improve the quality of preclinical studies of purported acute …

Modern robust statistical methods: an easy way to maximize the accuracy and power of your research.

DM Erceg-Hurn, VM Mirosevich - American Psychologist, 2008 - psycnet.apa.org
Classic parametric statistical significance tests, such as analysis of variance and least squares
regression, are widely used by researchers in many disciplines, including psychology. …

Goal setting as an outcome measure: a systematic review

J Hurn, I Kneebone, M Cropley - Clinical rehabilitation, 2006 - journals.sagepub.com
Background: Goal achievement has been considered to be an important measure of outcome
by clinicians working with patients in physical and neurological rehabilitation settings. This …

Poly (ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

MJL Eliasson, K Sampei, AS Mandir, PD Hurn… - Nature medicine, 1997 - nature.com
Nitric oxide (NO) and peroxynitrite, formed from NO and superoxide anion, have been implicated
as mediators of neuronal damage following focal ischemia, but their molecular targets …

Computational and inferential difficulties with mixture posterior distributions

G Celeux, M Hurn, CP Robert - Journal of the American Statistical …, 2000 - Taylor & Francis
This article deals with both exploration and interpretation problems related to posterior
distributions for mixture models. The specification of mixture posterior distributions means that the …

Gender-linked brain injury in experimental stroke

…, AS Kimes, ED London, RJ Traystman, PD Hurn - Stroke, 1998 - Am Heart Assoc
Background and Purpose—Premenopausal women are at lower risk than men for stroke,
but the comparative vulnerability to tissue injury once a cerebrovascular incident occurs is …

Poly (ADP-ribose)(PAR) polymer is a death signal

…, Z Zhang, RC Koehler, PD Hurn… - Proceedings of the …, 2006 - National Acad Sciences
Excessive activation of the nuclear enzyme, poly(ADP-ribose) polymerase-1 (PARP-1) plays
a prominent role in various of models of cellular injury. Here, we identify poly(ADP-ribose) (…

Experimental stroke induces massive, rapid activation of the peripheral immune system

…, AA Vandenbark, PD Hurn - Journal of Cerebral …, 2006 - journals.sagepub.com
Clinical experimental stroke induces injurious local brain inflammation. However, effects on
the peripheral immune system have not been well characterized. We quantified mRNA and …

An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain

…, T Otsuka, PD Hurn… - Proceedings of the …, 2003 - National Acad Sciences
The water channel AQP4 is concentrated in perivascular and subpial membrane domains of
brain astrocytes. These membranes form the interface between the neuropil and …

[PDF][PDF] Using learning analytics to predict (and improve) student success: A faculty perspective

B Dietz-Uhler, JE Hurn - Journal of interactive online learning, 2013 - ncolr.org
Learning analytics is receiving increased attention, in part because it offers to assist educational
institutions in increasing student retention, improving student success, and easing the …